Goal · Weight
Peptides for weight loss
GLP-1 receptor peptides are the most-requested compounds we carry, and for good reason — the research on appetite, glucose and body weight is striking. Here's how the main options differ and how to think about starting.
Peptides researched for this
- Tirzepatide — dual GIP/GLP-1; the most-used, well-documented option
- Retatrutide — triple-agonist; the newest, with the largest effects in trials
- Semaglutide — the proven GLP-1 workhorse with the longest track record
- Cagrilintide — an amylin analog often paired with a GLP-1 for synergy
How they work
GLP-1 (and GIP/glucagon) receptor agonists slow gastric emptying and act on appetite signaling in research models. The practical upshot people care about is reduced appetite and steadier energy. They're dosed weekly and titrated up slowly — the most common mistake is starting too high.
How to choose
Want the established, lower-cost option? Semaglutide. Want the current standard with strong data? Tirzepatide. Want the frontier with the biggest reported effect? Retatrutide. Our retatrutide vs tirzepatide guide goes deeper, and the dosing guide walks the titration ladders.
For research use only. Not for human consumption. Nothing here is medical advice — consult a licensed clinician for health decisions.